Lisinopril is an ACE inhibitor. It is used to treat high blood pressure, congestive heart failure in adults, or to improve survival after a heart attack. Find patient medical information for Lisinopril (Prinivil, Zestril, and Others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Learn about common and rare lisinopril side effects and what to do if they occur. Lisinopril is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. It is used in combination with other medications to treat heart failure. Lisinopril is also used to improve survival after a heart attack. Lisinopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] Lisinopril is an oral medication used to treat high blood pressure and heart failure. Learn about side effects, warnings, dosage, and more. Learn about the side effects of lisinopril, from common to rare, for consumers and healthcare professionals. View lisinopril information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, contra-indications and monitoring requirements. Lisinopril is a type of medicine called an ACE inhibitor which makes your blood vessels relax and widen. This helps to lower your blood pressure and makes it easier for your heart to pump blood around your body.